Pu Lab Publications 2020


Original Manuscripts

  • Wang, S., Li, Y., Xu, Y., Ma, Q., Lin, Z., Schlame, M., Bezzerides, V. J., Strathdee, D. & Pu, W. T. AAV Gene Therapy Prevents and Reverses Heart Failure in A Murine Knockout Model of Barth Syndrome. Circ. Res. (2020). doi:10.1161/CIRCRESAHA.119.315956. Article.

2020 Reviews/Editorials

  • Bezzerides, V. J. & Pu, W. T. Two sides of the same coin: new insights into mechanisms of ventricular fibrillation. Cardiovasc. Res. (2020). doi:10.1093/cvr/cvaa246
  • Wang, S., Guo, Y. & Pu, W. T. AAV Gene Transfer to the Heart. Methods Mol. Biol. 2158, 269–280 (2021). PDF.
  • Bezzerides, V. J., Prondzynski, M., Carrier, L. & Pu, W. T. Gene Therapy for Inherited Arrhythmias. Cardiovasc. Res. (2020). doi:10.1093/cvr/cvaa107 PDF.
  • Guo, Y. & Pu, W. T. Cardiomyocyte Maturation: New Phase in Development. Circ. Res. 126, 1086–1106 (2020). PDF. Article.
  • Lu, F. & Pu, W. T. The architecture and function of cardiac dyads. Biophys. Rev. (2020). doi:10.1007/s12551-020-00729-x. PDF.

Collaborative Work

  • Engelbrecht, E., Levesque, M. V., He, L., Vanlandewijck, M., Nitzsche, A., Niazi, H., Kuo, A., Singh, S. A., Aikawa, M., Holton, K., Proia, R. L., Kono, M., Pu, W. T., Camerer, E., Betsholtz, C. & Hla, T. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. Elife 9, (2020).
  • Chen, J., Ma, Q., King, J. S., Sun, Y., Xu, B., Zhang, X., Zohrabian, S., Guo, H., Cai, W., Li, G., Bruno, I., Cooke, J. P., Wang, C., Kontaridis, M., Wang, D.-Z., Luo, H., Pu, W. T. & Lin, Z. aYAP modRNA reduces cardiac inflammation and hypertrophy in a murine ischemia-reperfusion model. Life Sci Alliance 3, (2020).
  • Chen, J., Liang, X., Zhang, S., Wang, S., Garcia, S. P., Yan, P., Yu, H., Li, Z., Liu, L., Zhang, F., Wei, W., Le, H., Zhang, Y., Yuan, G.-C., Chen, S., Chen, Y., Sun, K., Pu, W. T. & Zhang, B. Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis. Cell Death Dis. 11, 75 (2020).
  • Konstantinidis, K., Bezzerides, V. J., Lai, L., Isbell, H. M., Wei, A.-C., Wu, Y., Viswanathan, M. C., Blum, I. D., Granger, J. M., Heims-Waldron, D., Zhang, D., Luczak, E. D., Murphy, K. R., Lu, F., Gratz, D. H., Manta, B., Wang, Q., Wang, Q., Kolodkin, A. L., Gladyshev, V. N., Hund, T. J., Pu, W. T., Wu, M. N., Cammarato, A., Bianchet, M. A., Shea, M. A., Levine, R. L. & Anderson, M. E. MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII. J. Clin. Invest. (2020). doi:10.1172/JCI133181
  • Zhang, F., Yan, P., Yu, H., Le, H., Li, Z., Chen, J., Liang, X., Wang, S., Wei, W., Liu, L., Zhang, Y., Ji, X., Xie, A., Chen, W., Han, Z., Pu, W. T., Chen, S., Chen, Y., Sun, K., Ge, B. & Zhang, B. LARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis. Cell Rep. 32, 108058 (2020).
  • Liu, J., Huang, Z.-P., Nie, M., Wang, G., Silva, W. J., Yang, Q., Freire, P. P., Hu, X., Chen, H., Deng, Z., Pu, W. T. & Wang, D.-Z. Regulation of myonuclear positioning and muscle function by the skeletal muscle-specific CIP protein. Proc. Natl. Acad. Sci. U. S. A. (2020). doi:10.1073/pnas.1922911117
  • Cai, W., Huang, J., Zhu, Q., Li, B. E., Seruggia, D., Zhou, P., Nguyen, M., Fujiwara, Y., Xie, H., Yang, Z., Hong, D., Ren, P., Xu, J., Pu, W. T., Yuan, G.-C. & Orkin, S. H. Enhancer dependence of cell-type-specific gene expression increases with developmental age. Proc. Natl. Acad. Sci. U. S. A. 117, 21450–21458 (2020).
  • Wang, K., Lin, R.-Z., Hong, X., Ng, A. H., Lee, C. N., Neumeyer, J., Wang, G., Wang, X., Ma, M., Pu, W. T., Church, G. M. & Melero-Martin, J. M. Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA. Sci Adv 6, eaba7606 (2020).
  • Guo, H., Lu, Y. W., Lin, Z., Huang, Z.-P., Liu, J., Wang, Y., Seok, H. Y., Hu, X., Ma, Q., Li, K., Kyselovic, J., Wang, Q., Lin, J. L.-C., Lin, J. J.-C., Cowan, D. B., Naya, F., Chen, Y., Pu, W. T. & Wang, D.-Z. Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart. Nat. Commun. 11, 4666 (2020).